Abstract Ubiquitin-specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUBs) in the ubiquitin-specific protease (USP) family.It is a key regulator of numerous cellular functions including immune response, cell cycle, DNA damage and repair, epigenetics, and several signaling pathways.USP7 acts by removing ubiquitin from the substrate
Jellyfish envenomation is a common problem in coastal areas all over the world; usually symptoms are self-limited with no long-lasting complications.Despite that, some jellyfish species, mainly populating the Indian Ocean, are renown to be potentially lethal and in some cases may cause severe myopathy.We report the first case of rhabdomyolysis foll
Background: Synchronous cancers have occasionally been detected at initial diagnosis among patients with breast and ovarian cancer.However, simultaneous coexistence and diagnosis of breast and pancreas cancer has not previously been reported.Case Report: Paternal transmission of a Panty Liners germline BRCA2 mutation to a patient who was diagnosed
A 22-year-old woman who was on sertraline 50 mg oral tablets once daily for 2 years for treatment of major depression took 30 such tablets (1500 mg) in a fit of rage, with a suicidal intent.She presented to the Emergency Department of a Tertiary Care Hospital with tachycardia, tachypnea, Cologne hypertension, tremors, agitation, confusion, vomiting